Against Me! have begun work on the album first announced last November. Titled Transgender Dysphoria Blues, the record marks the recorded debut of drummer Atom Willard (Angels and Airwaves, Rocket from the Crypt) and also represents a break from the band's major label contract.

Willard posted an Instagram of his drum setup in Laura Jane Grace's studio and Grace herself posted a photo of the studio's new console. It will be the first material from the band since the Russian Spies [7-inch] in 2011 and Total Clarity and White Crosses in 2010.